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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1954 1
1961 1
1963 1
1964 4
1965 1
1966 1
1967 2
1968 2
1969 2
1970 9
1971 2
1972 8
1973 2
1974 4
1975 28
1976 26
1977 33
1978 29
1979 46
1980 36
1981 52
1982 57
1983 59
1984 61
1985 97
1986 102
1987 102
1988 106
1989 143
1990 143
1991 148
1992 203
1993 198
1994 238
1995 289
1996 330
1997 404
1998 429
1999 494
2000 572
2001 626
2002 651
2003 781
2004 898
2005 1091
2006 1127
2007 1308
2008 1366
2009 1616
2010 1751
2011 1844
2012 2158
2013 2241
2014 2451
2015 2559
2016 2593
2017 2637
2018 2771
2019 3076
2020 3439
2021 3604
2022 3832
2023 3756
2024 1481

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48,464 results

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Page 1
Link Between m6A Modification and Cancers.
Liu ZX, Li LM, Sun HL, Liu SM. Liu ZX, et al. Front Bioeng Biotechnol. 2018 Jul 13;6:89. doi: 10.3389/fbioe.2018.00089. eCollection 2018. Front Bioeng Biotechnol. 2018. PMID: 30062093 Free PMC article. Review.
N6-methyladenosine (m6A) epitranscriptional modification has recently gained much attention. Through the development of m6A sequencing, the molecular mechanism and importance of m6A have been revealed. m6A is the most abundant internal modification in higher eukaryotic mRN …
N6-methyladenosine (m6A) epitranscriptional modification has recently gained much attention. Through the development of m6A sequencing, the …
Mechanism involved in insulin resistance via accumulation of beta-amyloid and neurofibrillary tangles: link between type 2 diabetes and Alzheimer's disease.
Rad SK, Arya A, Karimian H, Madhavan P, Rizwan F, Koshy S, Prabhu G. Rad SK, et al. Drug Des Devel Ther. 2018 Nov 22;12:3999-4021. doi: 10.2147/DDDT.S173970. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 30538427 Free PMC article. Review.
The pathophysiological link between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) has been suggested in several reports. Few findings suggest that T2DM has strong link in the development process of AD, and the complete mechanism is yet to be re …
The pathophysiological link between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) has been suggested in several report …
Phospholipid synthesis and transport in mammalian cells.
Vance JE. Vance JE. Traffic. 2015 Jan;16(1):1-18. doi: 10.1111/tra.12230. Epub 2014 Oct 15. Traffic. 2015. PMID: 25243850 Free article. Review.
In this article, pathways and subcellular sites of phospholipid synthesis in mammalian cells are summarized. A single, unifying mechanism does not explain the inter-organelle transport of all phospholipids. ...Recent studies suggest that protein complexes can form tethers …
In this article, pathways and subcellular sites of phospholipid synthesis in mammalian cells are summarized. A single, unifying mechanism
Toward a Mechanism-Driven Integrated Framework to Link Human Exposure to Multiple Toxic Metal(loid) Species with Environmental Diseases.
Gailer J. Gailer J. Int J Mol Sci. 2024 Mar 16;25(6):3393. doi: 10.3390/ijms25063393. Int J Mol Sci. 2024. PMID: 38542366 Free PMC article. Review.
Owing to the human exposure to multiple toxic metal(loid) species, the mechanism of chronic toxicity of each of these needs to be integrated into a framework to better define the underlying exposure-disease relationship. Accordingly, this review highlights some recent adva …
Owing to the human exposure to multiple toxic metal(loid) species, the mechanism of chronic toxicity of each of these needs to be int …
The missing link: a single unifying mechanism for diabetic complications.
Nishikawa T, Edelstein D, Brownlee M. Nishikawa T, et al. Kidney Int Suppl. 2000 Sep;77:S26-30. doi: 10.1046/j.1523-1755.2000.07705.x. Kidney Int Suppl. 2000. PMID: 10997687 Free article. Review.
Vascular endothelial cells are a major target of hyperglycemic damage, but the mechanisms underlying this damage remain incompletely understood. Three seemingly independent biochemical pathways are involved in the pathogenesis: glucose-induced activation of protein kinase …
Vascular endothelial cells are a major target of hyperglycemic damage, but the mechanisms underlying this damage remain incompletely …
Diabetes and cancer: Debating the link through Ca(2+)/cAMP signalling.
Bergantin LB. Bergantin LB. Cancer Lett. 2019 Apr 28;448:128-131. doi: 10.1016/j.canlet.2019.02.017. Epub 2019 Feb 13. Cancer Lett. 2019. PMID: 30771427 Review.
Diabetes has been clinically linked to an increased risk for developing several types of cancer. The cellular mechanisms involved in this link are still under intensive debate in literature. ...In this review, I have debated the possible involvement of Ca(2+)/cAMP s …
Diabetes has been clinically linked to an increased risk for developing several types of cancer. The cellular mechanisms involved in …
The Possible Causal Link of Periodontitis to Neuropsychiatric Disorders: More Than Psychosocial Mechanisms.
Hashioka S, Inoue K, Miyaoka T, Hayashida M, Wake R, Oh-Nishi A, Inagaki M. Hashioka S, et al. Int J Mol Sci. 2019 Jul 30;20(15):3723. doi: 10.3390/ijms20153723. Int J Mol Sci. 2019. PMID: 31366073 Free PMC article. Review.
Increasing evidence implies a possible causal link between periodontitis and neuropsychiatric disorders, such as Alzheimer's disease (AD) and major depression (MD). A possible mechanism underlying such a link can be explained by neuroinflammation induced by c …
Increasing evidence implies a possible causal link between periodontitis and neuropsychiatric disorders, such as Alzheimer's disease …
Depression and the Link with Cardiovascular Disease.
Dhar AK, Barton DA. Dhar AK, et al. Front Psychiatry. 2016 Mar 21;7:33. doi: 10.3389/fpsyt.2016.00033. eCollection 2016. Front Psychiatry. 2016. PMID: 27047396 Free PMC article. Review.
Much is known about the two individual clinical conditions; however, it is not until recently, biological mechanisms have been uncovered that link both MDD and CHD. The activation of stress pathways have been implicated as a neurochemical mechanism that links …
Much is known about the two individual clinical conditions; however, it is not until recently, biological mechanisms have been uncove …
Trimethylamine-N-oxide as One Hypothetical Link for the Relationship between Intestinal Microbiota and Cancer - Where We Are and Where Shall We Go?
Chan CWH, Law BMH, Waye MMY, Chan JYW, So WKW, Chow KM. Chan CWH, et al. J Cancer. 2019 Oct 8;10(23):5874-5882. doi: 10.7150/jca.31737. eCollection 2019. J Cancer. 2019. PMID: 31737123 Free PMC article. Review.
Previous epidemiological studies had provided evidence for a link between the microbial dysbiosis and cancer, particularly colorectal cancer (CRC), yet the molecular basis of this link remains elusive. ...The discovery could potentially provide an alternative explan …
Previous epidemiological studies had provided evidence for a link between the microbial dysbiosis and cancer, particularly colorectal …
Memory Control: A Fundamental Mechanism of Emotion Regulation.
Engen HG, Anderson MC. Engen HG, et al. Trends Cogn Sci. 2018 Nov;22(11):982-995. doi: 10.1016/j.tics.2018.07.015. Epub 2018 Aug 16. Trends Cogn Sci. 2018. PMID: 30122359 Free PMC article. Review.
Controlling the emotional impact of memories therefore poses a major emotion-regulation challenge, suggesting that there might be a hitherto unexplored link between the neurocognitive mechanisms underlying memory control (MC) and emotion regulation. We present here …
Controlling the emotional impact of memories therefore poses a major emotion-regulation challenge, suggesting that there might be a hitherto …
48,464 results
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